We use the best available evidence to develop recommendations that guide decisions in health, public health and social care. As well as considering the scientific value of evidence, we also follow a set of principles for making social value judgements.

All our guidance applies to Wales too. You can find out more on the Welsh Government website.


Our guidelines make evidence-based recommendations on a wide range of topics. These include preventing and managing specific conditions to planning broader services and interventions to improve the health of communities. They aim to promote integrated care where appropriate.

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Antimicrobial prescribing guidelines

Evidence-based guidelines for managing common infections in the context of tackling antimicrobial resistance, specifically in relation to bacterial infection and antibiotic use.

View antimicrobial prescribing guidelines

Technology appraisals guidance

This guidance assesses the clinical and cost effectiveness of health technologies, such as new pharmaceutical and biopharmaceutical products, but also includes procedures, devices and diagnostic agents. This ensures that all NHS patients have equitable access to the most clinically and cost-effective treatments that are available.

View technology appraisals guidance

Interventional procedures guidance

This guidance recommends whether interventional procedures, such as laser treatments for eye problems or deep brain stimulation for chronic pain, are effective and safe enough for use in the NHS.

View interventional procedures guidance

Medical technologies guidance

This guidance assesses specific technologies put forward to NICE by manufacturers. The ‘case for adoption’ recommendations are based on the claimed advantages of introducing the specific technology compared with current management of the condition.

View medical technologies guidance

Diagnostics guidance

This guidance focuses on the evaluation of innovative medical diagnostic technologies in order to ensure that the NHS is able to adopt clinically and cost-effective technologies rapidly and consistently.

View diagnostics guidance

Highly specialised technologies guidance

This guidance contains recommendations on the use of new and existing highly specialised medicines and treatments.

View highly specialised technologies guidance