Selective internal radiation therapy for primary hepatocellular carcinoma

Evidence-based recommendations on selective internal radiation therapy (SIRT) for primary hepatocellular carcinoma. This involves infusion of microspheres loaded with yttrium‑90, which aims to deliver radiation directly into the tumour, minimising the risk of radiation damage to healthy surrounding tissues.

NICE has also produced technology appraisal guidance on selective internal radiation therapies for treating hepatocellular carcinoma.

For recommendations on SIRT for intrahepatic cholangiocarcinoma, see our interventional procedures guidance on selective internal radiation therapy for unresectable primary intrahepatic cholangiocarcinoma.

Guidance development process

How we develop NICE interventional procedures guidance

Coding and clinical classification codes for this guidance.