Suggested remit: To appraise the clinical and cost effectiveness of trastuzumab deruxtecan within its marketing authorisation for treating HER2-low metastatic or unresectable breast cancer after chemotherapy.
Status In progress
Technology type Medicine
Decision Selected
Process STA Standard
ID number 3935

Provisional Schedule

Expected publication 15 November 2023

Project Team

Project lead Thomas Feist

Email enquiries

External Assessment Group School of Health and Related Research (ScHARR), University of Sheffield


Companies sponsors Daiichi Sankyo
Others Department of Health and Social Care
  NHS England
  Welsh Government
Patient carer groups Breast Cancer Now
Professional groups Association of Cancer Physicians
  Cancer Research UK
  Royal College of Physicians
  Royal College of Radiologists
Comparator companies Eisai
General commentators All Wales Therapeutics and Toxicology Centre
  British National Formulary (BNF)
  Department of Health, Social Services and Public Safety for Northern Ireland
  Healthcare Improvement Scotland
  Medicines and Healthcare products Regulatory Agency
  Scottish Medicines Consortium
  Welsh Health Specialised Services Committee
Relevant research groups Institute of Cancer Research


Key events during the development of the guidance:

Date Update
05 September 2023 Committee meeting: 1
06 January 2023 Invitation to participate
20 October 2022 - 17 November 2022 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators
20 October 2022 In progress. Scoping commenced.

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