Evidence-based recommendations on using immunohistochemistry or microsatellite instability testing to guide further testing for Lynch syndrome in people with colorectal cancer.

There is a flowchart showing the steps in the testing strategies.

Is this guidance up to date?

September 2022: We reviewed the latest evidence and plan to update the recommendations on testing for Lynch syndrome using next generation sequencing. For more information, see the review decision.

Guidance development process

How we develop NICE diagnostics guidance

  • National Institute for Health and Care Excellence (NICE)